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Your Mouth During Oral Cancer Treatment

Each year, many people are treated for oral cancer. Chemotherapy treatments for cancer and radiation treatment for head and neck cancer often cause oral complications. About half of chemotherapy patients experience oral complications, particularly those being treated for leukemia and those who receive bone marrow transplants.

These oral cancer complications significantly decrease quality of life and can lead to serious systemic problems, complications, septicemia, eating difficulty, nutritional deficiencies, and dehydration. The following are descriptions of oral problems that can occur with cancer treatment:

Infections of the oral cavity can be caused by the usual organisms found in the mouth or by opportunistic organisms not usually found in the mouth. These infections can lead to serious systemic infections. The risk is higher for individuals who have reduced numbers of circulating white blood cells (leukopenia).

Candidiasis is the overgrowth of candida albicans, a fungal organism that normally is found in the mouth.

Musositis is painful and causes problems with eating and speaking. Soft tissues are red, ulcerated, and inflamed. The oral cavity is susceptible to mucositis because of its high cell turnover.

Hemorrhage or bleeding of the oral cavity can occur when clotting factors are affected and during bone marrow suppression.

Xerostomia or dry mouth is associated with decreased, sticky, or thickened saliva. Dry soft tissues are more susceptible to pain, infection, and irritation. Dry mouth is associated with a high number of dental caries.

Altered taste or loss of taste is common and is related to the reduced saliva volume, as well as its altered consistency.

Developmental abnormalities such as altered craniofacial growth and dental/tooth deformities occur with cancer treatment during developmental periods.

Trismus, fibrosis, and scarring of the chewing muscles and temporomandibular joint (TMJ, the joint that moves the lower jaw) that were in the radiation field may make opening the mouth difficult and limited.

Osteoradionecrosis (soft tissue and bone necrosis) can be spontaneous or secondary to trauma, extractions, or dental prostheses. The radiated tissues have reduced blood vessels, decreased cells, and decreased oxygen that predisposes the tissues for years after the radiation therapy to this compromised state that makes oral surgical procedures risky. Therefore, prior to and post oral surgery, patients who have had head and neck radiation may require hyperbaric oxygen treatments and antibiotic therapy to prevent osteoradionecrosis.

Radiation dental caries is a term used for rapid tooth demineralization and severe cavities that occur with head and neck radiation, particularly when the parotid, submandibular, submental, or submaxillary salivary glands are in the radiation field.

Pain accompanies oral infection, mucositis, xerostomia, trismus, dental caries, osteoradionecrosis, candidiasis and dental caries.

To reduce risk for oral cancer complications, a dentist should perform a pretreatment oral examination, as well as necessary dental treatment before initiating chemotherapy or head and neck radiation. It is important that the dentist consult with the physician or oncologist before dental treatment because people who are about to undergo treatments for cancer may be immunosuppressed or thrombocytopenic (blood clotting disorder).

The goals of the dental examination and dental treatment are to eliminate existing or potential oral infection and potential for trauma. Infection, potential infection, and trauma can be associated with soft tissue lesions, decayed or broken teeth, dental implants with poor prognosis, periodontal disease, and poorly fitting full or partial dentures. The oral examination consists of hard and soft tissue examinations, periodontal assessment, and necessary radiographs. Since long-term effects of head and neck cancer radiation treatments will be harmful to the bone in the radiated area (field), patients who undergo head and neck radiation treatment should have teeth and implants with potential for future problems considered for extraction before the cancer treatment begins.

The patient's ability and interest in maintaining oral health, as well as the ability to comply with an oral cancer prevention routine, should be factors that are considered as the dentist develops and discusses dental treatment recommendations with the patient.

By Denise J. Fedele, DMD, MS

Dental Care: Frequently Asked Questions

Q. How does one care for primary teeth?

A. As soon as the first tooth erupts, primary teeth may be cleaned with a clean, wet wash cloth or wet gauze. The gums should also be gently wiped. If a toothbrush is used, it should be an appropriate size.

Q. Where does decay on the primary teeth occur most often?

A. With inappropriate or prolonged use of the baby bottle, decay may occur on the upper front teeth (incisors). The second most-often occurring site are the upper primary molars, which are found furthest back in the mouth. If there is no spacing between the primary teeth, there is a much greater chance of decay between the primary molars. These teeth should be flossed as soon as they come in.

Q. Why are dental sealants beneficial for children?

A. Dental sealants are protective coatings for the chewing surface of permanent molars. They protect the teeth from decay. Read on for more information.

Q. What is a dental implant?

A. A dental implant is a permanent artificial tooth replacement after a tooth loss.

Q. What is the procedure for receiving dental implants?

A. Dental implats are inserted surgically in two steps. The first step is to insert a "post" into or onto the jawbone. This post will then become the "anchor" for the artificial tooth that will be placed over the "post."

Q. How long is the procedure for dental implants?

A. Getting a dental implant is a two step process. Once te "post" is inserted into the jawbone, the patient will have between three and six months with a temporary restoration. During this period, the bone and gum area around the post will heal to create a strong and healthy bond. Once this bond is complete, an additional set of smaller posts is attached to the original post and then the artificial tooth is secured to the posts. The entire procedure could take anywhere from three to ten months.

Q. Can I eat regularly while the implants are bonding?

A. While th "post" is bonding with your jaw and gums, your dentist will place a temporary artificial tooth on the post. During the bonding period, you will need to eat soft foods.

Q. Do implants require special care?

A. Yes and No. Dental implants need to be brushed, flossed and checked regularly ba dentist, just as you would do with your regular teeth. But dental implants don't need special brushes or pastes.

Q. Can you eat and chew normally with dental implants?

A. Yes. Consider that natural teeth can absorb up to approximately 540 lbs. per square inch of biting pressure and properly placed dental implants can withstand up to approximately 450 lbs. per square inch of the same pressure.

Q. How long should a dental implant last?

A. With proper placement, excellent home care, regular dental visits, and good overall health, dental implants should be permanent.

Q. What are wisdom teeth?

A. Wisdom teeth are the third molars.

Q. Why is it necessary to remove wisdom teeth?

A. It is necessary to remove wisdom teeth to avoid problems, such as an impacted tooth destroying the second molar.

Q. Why do wisdom teeth cause problems?

A. Wisdom teeth generate problems because the shape of the modern human mouth is too small to accommodate these teeth, and they become impacted or unable to come in or move into their proper place.

Q. What problems occur from impacted third molars?

A. Partially erupted wisdom teeth are breeding grounds for bacteria and germs that may cause infection. Cysts and tumors may grow on trapped wisdom teeth.

Q. How is a wisdom tooth removed?

A. Wisdom teeth are remove by surgery. The gum tissue over the tooth is removed, the connective tissue is stripped gently away from the tooth and bone, the tooth is removed, and the gum sutured.

Q. When are lasers used in dentistry?

A. Lasers are used in oral surgery, gum surgery, tooth whitening, cancer sore treatment, and the treatment of gums that have been diseased.

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